WebNM_002591.4(PCK1):c.*349AT[4] AND Phosphoenolpyruvate carboxykinase (GTP) deficiency Clinical significance: Likely benign (Last evaluated: Jun 14, 2016) Review status: 1 star out of maximum of 4 stars WebPCK1, phosphoenolpyruvate carboxykinase 1 Vertebrate Orthologs 3 Vertebrate Orthology Source. Alliance of Genome Resources. Human Ortholog PCK1, phosphoenolpyruvate carboxykinase 1. Synonyms PCKDC, PEPCK1, PEPCKC, PEPCK-C Links HGNC:8724. NCBI Gene ID: 5105. neXtProt AC: NX_P35558. UniProt ...
Identification of phosphoenolpyruvate carboxykinase 1 as a
WebCompared with the Con group, the mRNA expression of glucose-6-phosphatase catalytic subunit (G6PC), phosphoenolpyruvate carboxykinase 1 (PCK1), and forkhead box protein O1 (FOXO1) in the PA group was significantly higher. The mRNA levels of the same genes were further increased in the Rev 100 µM group, but decreased in the Rev 20 µM group ... WebPhosphoenolpyruvate Carboxykinase 1 (PCK1) is a main control point for the regulation of gluconeogenesis. During gluconeogenesis PCK1 acts as the rate-limiting enzyme. PCK1 regulates the formation and maintenance of memory CH8(+) T-cells via gluconeogenesis. PCK1 aids in controlling the levels of metabolic intermediates in the citric acid cycle ... greetings holiday season
Human Gene PCK1 (ENST00000319441.6) from GENCODE V43
WebMar 21, 2024 · PCK1 (Phosphoenolpyruvate Carboxykinase 1) is a Protein Coding gene. Diseases associated with PCK1 include Phosphoenolpyruvate Carboxykinase Deficiency, … WebMar 26, 2024 · Phosphoenolpyruvate carboxykinase 1 (PCK1), a gluconeogenesis enzyme, was recently identified as an AKT-regulated protein kinase that phosphorylates INSIG1/2 to promote nuclear SREBP1-dependent lipogenesis. However, the relationship of this regulation with the progression of non-small-cell lung carcinoma (NSCLC) is unclear. It is classified under EC number 4.1.1. There are three main types, distinguished by the source of the energy to drive the reaction: • 4.1.1.32 – GTP (PCK1, PCK2) • 4.1.1.38 – diphosphate • 4.1.1.49 – ATP greetingshouse.co.uk